R&D Scientist

Date: Nov 22, 2023

Location: Tyrone, PA, US, 16686

Company: W. R. Grace & Co.

Requisition ID: 22481 

Built on talent, technology, and trust, Grace is a leading global supplier of catalysts and engineered materials. The company’s two industry-leading business segments—Catalysts Technologies and Materials Technologies—provide innovative products, technologies, and services that enhance the products and processes of our customers around the world. Grace employs approximately 4,300 people in over 30 countries.

Job Description

Grace is looking for a qualified and energetic chemist to join our R&D team at our Tyrone, Pennsylvania site.  Expertise in organic synthesis is a prerequisite with experience in amino acid and peptide synthesis and/or process scale-up is strongly preferred.  The Tyrone Site produces a portfolio of products including specialty pharmaceutical and agricultural chemicals, refinery catalysts, and performance chemicals.  Consisting of a pilot plant and custom manufacturing at the commercial volumes, the site is fully equipped to develop and manufacture custom chemicals.  Tyrone is located in central Pennsylvania within twenty-five minutes of Penn State University. The R&D Chemist will work on developing and improving processes for scale-up and plant production.  This position reports to the R&D team leader at Tyrone.


  • Responsible for defining, developing, and demonstrating commercially viable processes for custom products with a focus on developing economical and robust processes while minimizing waste streams.
  • Support production of new chemical entities during initial scale-up and process validation.
  • Perform experiments needed to evaluate and optimize a potential synthetic route in terms of its overall yield, purity, cost, and safety.
  • Develop and share ideas for synthesizing sophisticated organic molecules.  With an emphasis on applying innovative synthetic chemistry strategies and techniques.  
  • Work collaboratively with other departments including safety, engineering, analytical, and sourcing to introduce new chemical processes into full-scale production.
  • Write detailed development reports documenting the laboratory research.
  • Devise literature searches and utilize other resources that are needed in evaluating projects in terms of their costs, toxicity, safety, and relevant patent data.

Required Qualifications

  • PhD in organic chemistry or MS in chemistry with 3-5 years of experience in organic chemistry
  • Familiarity with modern laboratory instrumentation (NMR, HPLC, GC)
  • Experience with amino acids and peptide synthesis and/or process scale-up is preferred.


Preferred Qualifications

  • Sound understanding of synthetic organic chemistry fundamentals, technical knowledge, and experience in multi-step organic synthesis, process scale-up, troubleshooting, and optimization.
  • Ability to design and develop novel synthetic routes that can be scaled to plant assets.
  • Excellent communication, organization, planning, and interpersonal skills.  Ability to interact, lead, and collaborate within an interdisciplinary team environment.
  • Must be a highly productive, results-oriented individual capable of generating and implementing original ideas and solutions that contribute materially to the success of product manufacturing


Medical, Dental, Vision Insurance
Life Insurance and Disability
Grace Wellness Program
Flexible Workplace
Retirement Plans 
401(k) Company Match – Dollar to dollar up to the first 6%
Paid Vacation and Holidays
Parental Leave (salaried only)
Tuition Reimbursement
Company Donation Match Program


Be Authentic
Deliver Results
Engage and Include
Think Critically

Grace is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Grace via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Grace. No fee will be paid in the event the candidate is hired by Grace as a result of the referral or through other means.

Nearest Major Market: Altoona
Nearest Secondary Market: Johnstown